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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
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[1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found out that it promotes less energy uptake, the focus was switched to obesity. [11] Orlistat has a few ...
Lorcaserin. Lorcaserin, marketed under the brand name Belviq, [ 4][ 5] was a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus, a region of the brain which is known to control appetite. [ 6] It was approved in 2012, and in 2020, it was removed from ...
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The weight loss was comparable to that achieved with a 2.4 milligram dose of semaglutide injected once a week in the form of Wegovy over the same time frame, the company said in a statement.
Users of Alli and Xenical, beware -- the diet drugs may cause liver failure, according to the U.S. Food and Drug Administration. In a statement released on May 26, the government agency said ...
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