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  2. Prescription weight-loss drugs: Can they help you? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    Prescription weight-loss drugs that you can use for more than 12 weeks, called long-term use, lead to major weight loss compared with an inactive treatment that doesn't use medicine, called a placebo. The combination of weight-loss medicine and lifestyle changes leads to greater weight loss than do lifestyle changes alone.

  3. Vitamin B-12 injections for weight loss: Do they work? - Mayo...

    www.mayoclinic.org/healthy-lifestyle/weight-loss/expert...

    There's no solid proof that vitamin B-12 shots, also called injections, help you lose weight. Vitamin B-12 is a water-soluble B complex vitamin. It's found naturally in many foods, such as meat, fish and dairy products. Vitamin B-12 is added to some foods and is available as a dietary supplement. Health care providers commonly prescribe vitamin ...

  4. Semaglutide (Subcutaneous Route) Side Effects - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/semaglutide...

    Semaglutide injection is also used together with diet and exercise to help lose weight and keep the weight off in patients with at least one weight-related medical condition. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Solution; Before Using

  5. HCG diet: Is it safe and effective? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/expert...

    Answer From Katherine Zeratsky, R.D., L.D. No. The HCG diet isn't safe, and it doesn't lead to long-term weight loss. HCG stands for human chorionic gonadotropin. It's a hormone made in the body during pregnancy. Lab-made HCG is added to some weight-loss products that are sold without a prescription. The U.S. Food and Drug Administration (FDA ...

  6. GLP-1 agonists: Diabetes drugs and weight loss - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/type-2-diabetes/...

    These include canagliflozin (Invokana), ertugliflozin (Steglatro), dapagliflozin (Farxiga) and empagliflozin (Jardiance). Weight loss can vary depending on which GLP-1 drug you use and your dose. Studies have found that all GLP-1 drugs can lead to weight loss of about 10.5 to 15.8 pounds (4.8 to 7.2 kilograms, or kg) when using liraglutide.

  7. Weight-loss surgery: Is it an option for you? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    BMI is a formula that uses weight and height to estimate body fat. Weight-loss surgery might be an option for an adult with a BMI of 40 or higher. The surgery may also be an option for an adult who meets these three conditions: BMI of 35 or higher. At least one obesity-related medical condition. At least six months of supervised weight-loss ...

  8. Semaglutide (Subcutaneous Route) Proper Use - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/semaglutide...

    Adults and children 12 years of age and older—At first, 0.25 milligrams (mg) injected under the skin once a week for 4 weeks. Your doctor may increase your dose every 4 weeks. However the dose is usually not more than 2.4 mg once a week. Children younger than 12 years of age—Use and dose must be determined by your doctor.

  9. Alli weight-loss pill: Does it work? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    Alli is a 60-milligram, over-the-counter version of orlistat (Xenical), a 120-milligram prescription drug. Both Alli and Xenical are meant to be used as part of a weight-loss plan, along with a low-calorie, low-fat diet and regular physical activity. Alli is approved by the U.S. Food and Drug Administration for use in adults 18 and older who ...

  10. Tirzepatide (Subcutaneous Route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/tirzepatide...

    It is used together with diet and exercise to help control your blood sugar. Tirzapatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide injection is also used to help lose weight and keep the weight off in patients with obesity caused by certain conditions.

  11. Use of weight-loss pharmacotherapy in patients with cirrhosis and...

    www.mayoclinic.org/medical-professionals/digestive...

    In a review article published in Hepatology in 2021, Kymberly D. Watt, M.D., and co-authors discuss the use of four Food and Drug Administration (FDA)-approved weight-loss medications and three alternative medicine treatments in patients with cirrhosis and in liver transplant recipients.