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Beta blocker. Skeletal formula of propranolol, the first clinically successful beta blocker. Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms ( arrhythmia ), and to protect the heart from a second heart attack after a first heart attack ( secondary prevention ). [ 1]
Bisoprolol. Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [ 7] and used for cardiovascular diseases, [ 7] including tachyarrhythmias, high blood pressure, angina, and heart failure. [ 7][ 8] It is taken by mouth. [ 7]
The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors. [ 5] It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein that is expressed predominantly in cardiac tissue.
Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class. [2] It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, [2] [3] [4] as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous ...
1. -adrenergic agonist. β1-Adrenergic receptor agonists, also known as beta-1 agonists, are a class of drugs that bind selectively to the β 1 -adrenergic receptor. As a result, they act more selectively upon the heart. β-Adrenoceptors typically bind to norepinephrine release by sympathetic adrenergic nerves and to circulating epinephrine.
Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1 -adrenergic receptor and has no intrinsic sympathomimetic activity. [ 37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
The cardio-selective beta-1 blockers could cause adverse effects including bradycardia, reduced exercise ability, hypotension, atrioventricular nodal blockage and heart failure. [5] Other possible adverse effects include nausea and vomiting , abdominal discomfort , dizziness , weakness , headache , fatigue , and dryness in mouth and eye . [ 5 ]
Nebivolol is a beta blocker used to treat high blood pressure and heart failure. [5] As with other β-blockers, it is generally a less preferred treatment for high blood pressure. [6] It may be used by itself or with other blood pressure medication. [6] It is taken by mouth. [6] Common side effects include dizziness, feeling tired, nausea, and ...
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