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The contacts between the two proteins are shown as coloured patches. Protein–protein interactions ( PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.
Aquaporin. Aquaporins, also called water channels, are channel proteins from a larger family of major intrinsic proteins that form pores in the membrane of biological cells, mainly facilitating transport of water between cells. [ 1] The cell membranes of a variety of different bacteria, fungi, animal and plant cells contain aquaporins through ...
Channelopathies are a group of diseases caused by the dysfunction of ion channel subunits or their interacting proteins. These diseases can be inherited or acquired by other disorders, drugs, or toxins. Mutations in genes encoding ion channels, which impair channel function, are the most common cause of channelopathies. [ 1]
In biology literature, the term topology is also used to refer to mutual orientation of regular secondary structures, such as alpha-helices and beta strands in protein structure [3] [1]. For example, two adjacent interacting alpha-helices or beta-strands can go in the same or in opposite directions. Topology diagrams of different proteins with ...
Facilitated diffusion is one form of diffusion and it is important in several metabolic processes. Facilitated diffusion is the main mechanism behind the binding of Transcription Factors (TFs) to designated target sites on the DNA molecule. The in vitro model, which is a very well known method of facilitated diffusion, that takes place outside ...
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. [ 1] The changes elicited by ligand binding (or signal sensing) in a receptor give ...
Mellanox Delivers Enhanced Worldwide Channel Partner Program Award-winning program offers partners tools, training and blueprints for success in high-growth markets SUNNYVALE, Calif. & YOKNEAM ...
A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function. Examples of common classes of biological targets are proteins and nucleic acids. The definition is context-dependent, and can refer to the ...