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A hitter with a .400 on-base percentage is considered to be great [2] and rare; [3] only 61 players in MLB history with at least 3,000 career plate appearances (PA) have maintained such an OBP. Left fielder Ted Williams, who played 19 seasons for the Boston Red Sox, has the highest career on-base percentage, .4817, in MLB history. [4]
The top 100 Major League Baseball players in career OPS with at least 3,000 career plate appearances, as of August 17, 2024, are: Aaron Judge, the active leader and 11th all-time in career OPS. Rank
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Rank amongst leaders in career strikeouts. A blank field indicates a tie. Player (2024 Ks) Number of strikeouts during the 2024 Major League Baseball season. K: Total career strikeouts. * Denotes elected to National Baseball Hall of Fame. Bold: Denotes active player. [note 1]
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Optimer structure with non target binding groups removed for improved Optimer performance and manufacturability. Optimer ligands are short synthetic oligonucleotide molecules composed of DNA or RNA that bind to a specific target molecule. They are engineered to bind their target molecules with affinity typically in the low nanomolar range. [1]
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