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Optimer Pharmaceuticals, Inc. was founded in 1998 and registered in the state of Delaware. Corporate and R&D headquarters were located in San Diego, California until 2011. CEO Michael Nientse Chang founded, funded and built the company with his wife, Tessie Mary Che, who was COO from 1998 to 2011. From 2007 to 2013, Optimer Pharmaceuticals was ...
Optimer structure with non target binding groups removed for improved Optimer performance and manufacturability. Optimer ligands are short synthetic oligonucleotide molecules composed of DNA or RNA that bind to a specific target molecule. They are engineered to bind their target molecules with affinity typically in the low nanomolar range. [1]
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t. e. Search engine optimization ( SEO) is the process of improving the quality and quantity of website traffic to a website or a web page from search engines. [ 1][ 2] SEO targets unpaid traffic (known as "natural" or "organic" results) rather than direct traffic or paid traffic. Unpaid traffic may originate from different kinds of searches ...
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The query optimizer attempts to determine the most efficient way to execute a given query by considering the possible query plans. [ 1 ] Generally, the query optimizer cannot be accessed directly by users: once queries are submitted to the database server, and parsed by the parser, they are then passed to the query optimizer where optimization ...