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Duloxetine, sold under the brand name Cymbalta among others, [ 1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [ 7][ 8] It is taken by mouth. [ 7]
This new approval allows Lilly to market Cymbalta for pain. Further, Cymbalta, which accounts for 14% of Lilly's revenue, is set to lose its patent protection in 2013.
Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by Eli Lilly, a pharmaceutical chemist and Union Army veteran of the American Civil War for whom the company was later named.
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [ 5] The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance ...
The patent cliff continues to punish global pharmaceutical giant Eli Lilly , with the company losing patent protection on depression and fibromyalgia drug Cymbalta in December, and with ...
The early read on how painful Cymbalta's patent expiration will be on Eli Lilly this year isn't promising. After losing exclusivity in December, fourth quarter sales of Cymbalta tumbled 38% to ...
As expected, the Food and Drug Administration has approved the first generic versions of Eli Lilly's depression drug Cymbalta. Six versions in fact. On Wednesday, Aurobindo Pharma, Dr. Reddy's ...
Baricitinib is a Janus kinase (JAK) inhibitor that reversibly inhibits Janus kinase 1 with a half maximal inhibitory concentration (IC 50) of 5.9 nM and Janus kinase 2 with an IC 50 of 5.7 nM. Tyrosine kinase 2, which belongs to the same enzyme family, is affected less (IC 50 = 53 nM), and Janus kinase 3 far less (IC 50 > 400 nM).