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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Examples of such medications include the Orlistat, which was first prescribed in 1998. In 2009, it became an over-the-counter drug after obtaining consent from the European Medicines Agency . In clinical trials, patients prescribed with Orlistat (120 mg) showed better weight loss than those without (8.76 kg vs 5.81 kg) in one year. [14]
It is strongly dose-dependent: for the immediate release preparation, the seizure incidence is 0.4% at the dose 300–450 mg per day; the incidence climbs almost ten-fold for the higher than recommended dose of 600 mg. [23] For comparison, the incidence of unprovoked seizure in the general population is 0.07–0.09%, and the risk of seizure for ...
Injection site reactions ( ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration .
e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...
Summary. Description. Orlistat structure.svg. English: Skeletal formula of orlistat —an anti-obesity medication. Original brand name Xenical®. Created with ChemDoodle 7.0.2 and Adobe Illustrator CC 2015. Date. 2 July 2015.
New artifacts have been found on the legendary Spanish galleon San Jose, with the wreckage believed to be holding treasures worth billions of dollars.
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