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Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF) is increasingly being recognized. [ 2]
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue ( fibrosis) and regenerative nodules as a result of chronic liver disease. [ 6 ][ 7 ][ 8 ] Damage to the liver leads to repair of liver tissue ...
Alcohol-Associated Liver Disease Mortality Increased From 2017 to 2020 and Accelerated During the COVID-19 Pandemic. Clinical Gastroenterology and Hepatology . Alcohol and the Human Body.
Liver disease. Liver disease, or hepatic disease, is any of many diseases of the liver. [ 1] If long-lasting it is termed chronic liver disease. [ 3] Although the diseases differ in detail, liver diseases often have features in common.
Hepatitis. Alcoholic hepatitis as seen with a microscope, showing fatty changes (white circles), remnants of dead liver cells, and Mallory bodies (twisted-rope shaped inclusions within some liver cells). ( H&E stain) Specialty. Infectious disease, gastroenterology, hepatology. Symptoms.
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