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A hitter with a .400 on-base percentage is considered to be great [2] and rare; [3] only 61 players in MLB history with at least 3,000 career plate appearances (PA) have maintained such an OBP. Left fielder Ted Williams , who played 19 seasons for the Boston Red Sox , has the highest career on-base percentage, .4817, in MLB history. [ 4 ]
Hank Aaron is the career leader in total bases with 6,856. Albert Pujols (6,211), Stan Musial (6,134), and Willie Mays (6,080) are the only other players with at least 6,000 career total bases. As of August 17, 2024, no active players are in the top 100 for career total bases.
Optimer structure with non target binding groups removed for improved Optimer performance and manufacturability. Optimer ligands are short synthetic oligonucleotide molecules composed of DNA or RNA that bind to a specific target molecule. They are engineered to bind their target molecules with affinity typically in the low nanomolar range. [1]
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Optimer Pharmaceuticals Inc ( Nasdaq : OPTR) was a biopharmaceutical company, originally headquartered in San Diego, California, and later moved to Jersey City, New Jersey, United States. The company focused on developing specialty drugs to treat gastrointestinal infections and related diseases. In 2011, it received regulatory approval for the ...