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  2. Asthma - Wikipedia

    en.wikipedia.org/wiki/Asthma

    Asthma is a long-term inflammatory disease of the airways of the lungs. [ 4] It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. [ 9][ 10] Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. [ 3]

  3. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    In 1890 adrenalin was first given to asthma patients orally. It had little or no effect because it is metabolized in the digestive tract and is deactivated. In 1930 epinephrine was for the first time given subcutaneously and was discovered to have a positive effect on asthma. [ 1 ]

  4. History of catecholamine research - Wikipedia

    en.wikipedia.org/wiki/History_of_catecholamine...

    In 1903 adrenaline, meanwhile purified, was first used in asthma. The use was based, not on the bronchodilator effect, which was discovered later, [15] [16] but on the vasoconstrictor effect, which was hoped to alleviate the “turgidity of the bronchial mucosa” – presumably vascular congestion and edema. [17]

  5. Salbutamol - Wikipedia

    en.wikipedia.org/wiki/Salbutamol

    Salbutamol. Salbutamol, also known as albuterol and sold under the brand name Ventolin among others, [ 1] is a medication that opens up the medium and large airways in the lungs. [ 8] It is a short-acting β 2 adrenergic receptor agonist that causes relaxation of airway smooth muscle. [ 8] It is used to treat asthma, including asthma attacks ...

  6. Respiratory syncytial virus - Wikipedia

    en.wikipedia.org/wiki/Respiratory_syncytial_virus

    Respiratory syncytial virus (RSV) was discovered in 1956 from a laboratory chimpanzee with upper respiratory tract disease. When 14 chimpanzees were observed with cold-like symptoms, Morris and colleagues discovered a new virus they initially named the "chimpanzee coryza agent" (CCA).

  7. History and culture of substituted amphetamines - Wikipedia

    en.wikipedia.org/wiki/History_and_culture_of...

    Such methamphetamine labs are sometimes discovered when emergency personnel respond to fires due to improper handling of volatile or flammable materials. [121] [122] Single-pot "shake and bake" syntheses are particularly prone to explode and ignite, and, when abandoned, still pose a severe hazard to firefighters. [122]

  8. 1950 Wynder and Graham Study - Wikipedia

    en.wikipedia.org/wiki/1950_Wynder_and_Graham_Study

    Statistically, it was rare to find cases of epidermoid or undifferentiated carcinoma in males who haven’t been heavy smokers. Moreover, 96.1% of people with lung cancer smoked for over 20 years, which leads the researchers to hypothesize a 10-year or more lag time between starting smoking and exhibiting the first signs of cancer.

  9. Asthma UK - Wikipedia

    en.wikipedia.org/wiki/Asthma_UK

    The Asthma Research Council was started in 1927. At that time the annual income was between £1,000 and £4,000 a year. One of the first donations was used to pay for special asthma clinics at Guy's Hospital and Great Ormond Street Hospital. In 1989 it became the National Asthma Campaign and in 2004, when support for people with asthma had ...

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