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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
[37] [159] However, a significant incidence of seizures at the originally recommended dosage (400–600 mg/day) caused the withdrawal of the drug in 1986. Subsequently, the risk of seizures was found to be highly dose-dependent, and bupropion was re-introduced to the market in 1989 with a lower maximum recommended daily dose of 450 mg/day. [160]
e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...
There were no obvious differences in effectiveness of raloxifene in the MORE trial for prevention of breast cancer at a dosage of 60 mg/m 2 /day relative to 120 mg/m 2 /day. [13] In the Study of Tamoxifen and Raloxifene (STAR) trial, 60 mg/day raloxifene was 78% as effective as 20 mg/day tamoxifen in preventing non-invasive breast cancer. [ 14 ]
Examples of such medications include the Orlistat, which was first prescribed in 1998. In 2009, it became an over-the-counter drug after obtaining consent from the European Medicines Agency . In clinical trials, patients prescribed with Orlistat (120 mg) showed better weight loss than those without (8.76 kg vs 5.81 kg) in one year. [14]
Wed, Jun 5, 2024 · 2 min read. SOPA Images via Getty Images. Australia's independent regulator for online safety has ended its bid to remove a violent video from X (formerly Twitter). On April 15 ...
Loratadine. Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [ 5] This includes allergic rhinitis (hay fever) and hives. [ 5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [ 5]