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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Legal status. In Wikidata. Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. The primary role of lipase inhibitors is to decrease the gastrointestinal absorption of fats. Fats then tend to be excreted in feces rather than being absorbed to be ...
Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
Therefore, it is recommended to take a multiple-vitamin supplement during orlistat therapy. [9] [12] Cetilistat, a new lipase inhibitor, is an experimental drug for obesity. In October 2016 the drug was still in clinical trials. [13] Cetilistat was developed to overcome the adverse effects on the gastrointestinal tract of orlistat.
It is strongly dose-dependent: for the immediate release preparation, the seizure incidence is 0.4% at the dose 300–450 mg per day; the incidence climbs almost ten-fold for the higher than recommended dose of 600 mg. [23] For comparison, the incidence of unprovoked seizure in the general population is 0.07–0.09%, and the risk of seizure for ...
Loratadine. Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [ 5] This includes allergic rhinitis (hay fever) and hives. [ 5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [ 5]
A healthcare provider may get you started on a 0.25-milligram (mg) dose of Ozempic. This could increase to 0.5 milligrams after four weeks, 1 milligram after another four weeks and 2 milligrams ...
e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...
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