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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
[5] [8] [9] For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. [1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found ...
Steatorrhea. Steatorrhea. Specialty. Gastroenterology, general surgery. Steatorrhea (or steatorrhoea) is the presence of excess fat in feces. Stools may be bulky and difficult to flush, have a pale and oily appearance, and can be especially foul-smelling. [ 1] An oily anal leakage or some level of fecal incontinence may occur.
Here’s the TL;DR on metformin and weight loss: It may take weeks or months to see weight loss on metformin . Research shows people lose weight after three to six months of treatment. But don’t ...
The findings are even more significant because older weight-loss medications, like phentermine or orlistat, have not been shown to protect against serious heart problems, said Dr. Susan Spratt, an ...
Studies have shown that lipase inhibitors work optimally when 40% of an individual's daily caloric intake is obtained from fat. [ 1 ] [ clarification needed ] Orlistat tends to block absorption of 30% of total fat intake from a meal, as orlistat passes out of the digestive tract more rapidly than fat does.
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