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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Studies have shown that lipase inhibitors work optimally when 40% of an individual's daily caloric intake is obtained from fat. [ 1 ] [ clarification needed ] Orlistat tends to block absorption of 30% of total fat intake from a meal, as orlistat passes out of the digestive tract more rapidly than fat does.
[5] [8] [9] For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. [1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found ...
Yikes. Having said that, some supplements show promise, including magnesium, caffeine, green tea, protein, fiber and vitamin B12. Below, we’ll cover the best weight loss supplements for women ...
We have data that many macronutrient restrictive diets work for weight loss. Some feel eating fewer carbs is best, but one can lose weight by eating less fat only or less protein only, too. Diets ...
The findings are even more significant because older weight-loss medications, like phentermine or orlistat, have not been shown to protect against serious heart problems, said Dr. Susan Spratt, an ...
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