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Hepatorenal syndrome (often abbreviated HRS) is a life-threatening medical condition that consists of rapid deterioration in kidney function in individuals with cirrhosis or fulminant liver failure. HRS is usually fatal unless a liver transplant is performed, although various treatments, such as dialysis, can prevent advancement of the condition.
Liver failure. Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF) is increasingly being recognized. [ 2]
Kidney failure, also known as end-stage renal disease ( ESRD ), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. [ 2] Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney ...
Treatment. Liver transplant. Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue ( fibrosis) and regenerative nodules as a result of chronic liver disease. [ 6 ][ 7 ][ 8 ] Damage to the liver leads to repair of liver tissue ...
hepatic coma. [ 3] Hepatic encephalopathy ( HE) is an altered level of consciousness as a result of liver failure. [ 2] Its onset may be gradual or sudden. [ 2] Other symptoms may include movement problems, changes in mood, or changes in personality. [ 2] In the advanced stages it can result in a coma.
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