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On 23 January 2006, an FDA advisory panel voted 11 to 3 to recommend the approval of an OTC formulation of orlistat, to be sold under the brand name Alli by GlaxoSmithKline. [41] Approval was granted on 7 February 2007, [42] and Alli became the first weight loss drug officially sanctioned by the U.S. government for over-the-counter use. [43]
Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...
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Zone 5 uses eight 2-digit codes (51–58) and two sets of 3-digit codes (50x, 59x) to serve South and Central America. Zone 6 uses seven 2-digit codes (60–66) and three sets of 3-digit codes (67x–69x) to serve Southeast Asia and Oceania. Zone 7 uses an integrated numbering plan; two digits (7x) determine the area served: Russia or Kazakhstan.
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