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2. Orlistat - Wikipedia

   en.wikipedia.org/wiki/Orlistat

   Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

3. Discovery and development of gastrointestinal lipase ...

   en.wikipedia.org/wiki/Discovery_and_development...

   [5] [8] [9] For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. [1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found ...

4. Sibutramine - Wikipedia

   en.wikipedia.org/wiki/Sibutramine

   Sibutramine is a serotonin–norepinephrine reuptake inhibitor (SNRI) that, in humans, reduces the reuptake of norepinephrine (by ~73%), serotonin (by ~54%), and dopamine (by ~16%), [ 22] thereby increasing the levels of these substances in synaptic clefts and helping enhance satiety; the serotonergic action, in particular, is thought to ...

5. What Is the Strongest Weight Loss Prescription Pill? - AOL

   www.aol.com/strongest-weight-loss-prescription...

   Orlistat (Xenical, Alli). Orlistat works by preventing your body from absorbing dietary fats. It inhibits lipase, an enzyme in the intestine that breaks down fat molecules. This leads to reduced ...

6. Anti-obesity medication - Wikipedia

   en.wikipedia.org/wiki/Anti-obesity_medication

   e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...

7. Lilly beefs up bowel disease drug portfolio with $3.2 billion ...

   www.aol.com/news/eli-lilly-buy-bowel-disease...

   Shares of Waltham, Massachusetts-based Morphic surged 76% to $56.15 in premarket trading on Lilly's offer of $57 per share, which represents a 79% premium to stock's last closing price.