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Soursop. Soursop (also called graviola, guyabano, and in Latin America guanábana) is the fruit of Annona muricata, a broadleaf, flowering, evergreen tree. [ 4][ 5] It is native to the tropical regions of the Americas and the Caribbean and is widely propagated. [ 6] It is in the same genus, Annona, as cherimoya and is in the Annonaceae family.
Annonacin is a chemical compound with toxic effects, especially in the nervous system, found in some fruits such as the paw paw, custard apples, soursop, and others from the family Annonaceae. It is a member of the class of compounds known as acetogenins. Annonacin-containing fruit products are regularly consumed throughout the West Indies for ...
Alcohol-related brain damage[ 1][ 2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe, [ 3] limbic system, and cerebellum, [ 4] with widespread ...
Acetogenin. Acetogenins are a class of polyketide natural products found in plants of the family Annonaceae. They are characterized by linear 32- or 34-carbon chains containing oxygenated functional groups including hydroxyls, ketones, epoxides, tetrahydrofurans and tetrahydropyrans. They are often terminated with a lactone or butenolide. [1]
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The long-term impact of alcohol on the brain has become a growing area of research focus. While researchers have found that moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence, [ 1] excessive alcohol consumption is associated with widespread and significant brain lesions.
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system. [1] It occurs when exposure to a substance – specifically, a neurotoxin or neurotoxicant – alters the normal activity of the nervous system in such a ...
The Neurotoxicity section states: "The compound annonacin, which is contained in the fruit and seeds...". These statements are inconsistent in describing the location of annonacin in the fruit; is it in the seeds only or in both the fruit and seeds? The article defines Soursop as "the fruit of Annona muricata".
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