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  2. Pain and pleasure - Wikipedia

    en.wikipedia.org/wiki/Pain_and_pleasure

    Deep brain stimulation has been shown in several studies to both induce pleasure or even addiction as well as ameliorate pain. For chronic pain, lower frequencies (about 5–50 Hz) have produced analgesic effects, whereas higher frequencies (about 120–180 Hz) have alleviated or stopped pyramidal tremors in Parkinson's patients. [18]

  3. This Is What Happens to Your Brain When You Orgasm ... - AOL

    www.aol.com/entertainment/happens-brain-orgasm...

    Bottom line: If you’re struggling with low desire, start masturbating—the more orgasms you have, the stronger your libido will be. 8. Neural Connections Are Strengthened. Finally, every time ...

  4. Endorphins - Wikipedia

    en.wikipedia.org/wiki/Endorphins

    Endorphins (contracted from endogenous morphine) [1] [2] [3] are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing. They are produced and stored in the pituitary gland of the brain. Endorphins are endogenous painkillers often produced in the brain and adrenal medulla during physical exercise or ...

  5. Periaqueductal gray - Wikipedia

    en.wikipedia.org/wiki/Periaqueductal_gray

    The periaqueductal gray ( PAG, also known as the central gray) is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to threatening stimuli. [1] [2] PAG is also the primary control center for descending pain modulation. It has enkephalin -producing cells that suppress pain.

  6. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    The gate control theory of pain describes how non-painful sensations can override and reduce painful sensations. A painful, nociceptive stimulus stimulates primary afferent fibers and travels to the brain via transmission cells. Increasing activity of the transmission cells results in increased perceived pain. Conversely, decreasing activity of ...

  7. Insular cortex - Wikipedia

    en.wikipedia.org/wiki/Insular_cortex

    Anatomical terms of neuroanatomy. [ edit on Wikidata] The insular cortex (also insula and insular lobe) is a portion of the cerebral cortex folded deep within the lateral sulcus (the fissure separating the temporal lobe from the parietal and frontal lobes) within each hemisphere of the mammalian brain .

  8. Pain - Wikipedia

    en.wikipedia.org/wiki/Pain

    Medication. Analgesic. Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage."

  9. Psychological pain - Wikipedia

    en.wikipedia.org/wiki/Psychological_pain

    Psychological pain, mental pain, or emotional pain is an unpleasant feeling (a suffering) of a psychological, non-physical origin. A pioneer in the field of suicidology, Edwin S. Shneidman, described it as "how much you hurt as a human being. It is mental suffering; mental torment." [1] There is no shortage in the many ways psychological pain ...