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1q21.1 duplication syndrome arises from microduplications of the BP3-BP4 region, containing at least seven genes and a minimum duplicated region of ~1.2 Mb of unique DNA sequence. [ 7] 1q21.1 duplication syndrome has an autosomal dominant inheritance pattern, where 18–50% of deletions happen de novo and 50–82% are inherited from their parents.
2015 (Monday) 2014 (Sunday) September 21 is the 264th day of the year (265th in leap years) in the Gregorian calendar; 101 days remain until the end of the year.