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Optimer Pharmaceuticals, Inc. was founded in 1998 and registered in the state of Delaware. Corporate and R&D headquarters were located in San Diego, California until 2011. CEO Michael Nientse Chang founded, funded and built the company with his wife, Tessie Mary Che, who was COO from 1998 to 2011. From 2007 to 2013, Optimer Pharmaceuticals was ...
For the network using the phone number, see 988 Suicide & Crisis Lifeline. " 1-800-273-8255 " (also known simply as " 1-800 ") is a song by American rapper Logic featuring Canadian singer-songwriter Alessia Cara and American singer-songwriter Khalid. It was released on April 27, 2017, through Visionary Music Group and Def Jam Recordings, as the ...
Connie Mack in 1916. Connie Mack is the all-time leader in career wins and losses by a manager. This article contains a list of all Major League Baseball managers with at least 1,000 career regular season wins and a list of managers who have regular season win percentages of at least .540 in at least 450 games (slightly less than three full seasons). [1]
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Optimer structure with non target binding groups removed for improved Optimer performance and manufacturability. Optimer ligands are short synthetic oligonucleotide molecules composed of DNA or RNA that bind to a specific target molecule. They are engineered to bind their target molecules with affinity typically in the low nanomolar range. [1]
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Salvador Pérez, the active leader in career games played as a catcher and is 64th all-time. Yadier Molina holds the National League career record. Carlton Fisk holds the American League career record. Gary Carter held the National League record for 31 years. Al López held the major league record for 42 years.