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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Studies have shown that lipase inhibitors work optimally when 40% of an individual's daily caloric intake is obtained from fat. [ 1 ] [ clarification needed ] Orlistat tends to block absorption of 30% of total fat intake from a meal, as orlistat passes out of the digestive tract more rapidly than fat does.
[5] [8] [9] For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. [1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found ...
The definition of "healthy weight" for people ages 60 and up can get murky. Doctors often use Body Mass Index (BMI) , which defines overweight as having a BMI of 25.0 to 29.9 and obese as 30.0 or ...
See a Registered Dietitian. Working with a registered dietitian, an R.D. or R.D.N., can make the diet planning side of weight loss a whole lot easier.
The weight-loss drug Wegovy can reduce the risk of heart attacks and strokes by 20% in adults with heart disease and obesity, according to new research.. The trial is the first to show that a ...
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