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Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue ( fibrosis) and regenerative nodules as a result of chronic liver disease. [ 6 ][ 7 ][ 8 ] Damage to the liver leads to repair of liver tissue ...
Liver failure. Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF) is increasingly being recognized. [ 2]
The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease.It was initially developed to predict mortality within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, [1] and was subsequently found to be useful in determining prognosis and prioritizing for receipt of ...
In medicine, specifically gastroenterology, the Child–Pugh score (or the Child–Turcotte–Pugh ( CTP) score or Child Criteria) is used to assess the prognosis of chronic liver disease, mainly cirrhosis. Although it was originally used to predict mortality during surgery, it is now used to determine the prognosis, as well as the required ...
1 in 3,000–4,000 people. Primary biliary cholangitis ( PBC ), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [ 1][ 2][ 3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.
In advanced stages of chronic hepatitis C, cirrhosis—or scarring of the liver—is common. “Once you develop cirrhosis, it is difficult to reverse,” says Dr. Menon.
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