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On-board diagnostics. Various views of a "MaxScan OE509" – a fairly typical onboard diagnostics (OBD) scanner, 2015. On-board diagnostics ( OBD) is a term referring to a vehicle's self-diagnostic and reporting capability. In the United States, this capability is a requirement to comply with federal emissions standards to detect failures that ...
C-reactive protein. C-reactive protein ( CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells.
In contrast, C-reactive protein (with a half-life of 6–8 hours) rises rapidly and can quickly return to within the normal range if treatment is employed. For example, in active systemic lupus erythematosus, one may find a raised ESR but normal C-reactive protein. [citation needed] They may also indicate liver failure. [11]
The activated protein C resistance ( APCR) test is a coagulation test used in the evaluation and diagnosis of activated protein C (APC) resistance, a form of hypercoagulability. [1] [2] Hereditary APC resistance is usually caused by the factor V Leiden mutation, whereas acquired APC resistance has been linked to antiphospholipid antibodies ...
OBD-II PIDs (On-board diagnostics Parameter IDs) are codes used to request data from a vehicle, used as a diagnostic tool. SAE standard J1979 defines many OBD-II PIDs. All on-road vehicles and trucks sold in North America are required to support a subset of these codes, primarily for state mandated emissions inspections .
Protein C. Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, [ 5]: 6822 [ 6] is a zymogen, that is, an inactive enzyme. The activated form plays an important role in regulating anticoagulation, inflammation, and cell death and maintaining the permeability of blood vessel walls in humans and other animals.
A normal C-reactive protein can be used to exclude elevated ferritin caused by acute phase reactions. [citation needed] Ferritin has been shown to be elevated in some cases of COVID-19 and may correlate with worse clinical outcome. [40] [41] Ferritin and IL-6 are considered to be possible immunological biomarkers for severe and fatal cases of ...
For instance, up to 80% of those with SLE will have a positive double strand anti-double stranded DNA (anti-dsDNA) autoantibody test, but only about 25–30% will have a positive RNP. Some individuals who do have an autoimmune disorder will have negative autoantibody test results, but at a later date – as the disorder progresses - the ...