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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
AOH1996 was created to target a post-translationally modified isoform of PCNA, termed caPCNA, which is preferentially found in cancer cells. PCNA is crucial in the body for DNA repair , but targeting it is difficult because of its role in healthy cells.
Steatorrhea. Specialty. Gastroenterology, general surgery. Steatorrhea (or steatorrhoea) is the presence of excess fat in feces. Stools may be bulky and difficult to flush, have a pale and oily appearance, and can be especially foul-smelling. [ 1] An oily anal leakage or some level of fecal incontinence may occur.
Users of Alli and Xenical, beware -- the diet drugs may cause liver failure, according to the U.S. Food and Drug Administration. In a statement released on May 26, the government agency said ...
Orlistat (Xenical, Alli). Orlistat works by preventing your body from absorbing dietary fats. It inhibits lipase, an enzyme in the intestine that breaks down fat molecules. This leads to reduced ...
While private Medicare Advantage plans can include more types of coverage than traditional Medicare, it doesn't necessarily deliver more or better care. Learn how to weigh the pros and cons before ...
Weight loss in those receiving the fen-phen combination was significantly greater (8.4±1.1 kg) than in those receiving placebo (4.4±0.9 kg) and equivalent to that of those receiving fenfluramine (7.5±1.2 kg) or phentermine alone (10.0±1.2 kg). This amounts to an additional weight loss of 4±2 kg over the course of 24 weeks.
U.S. Olympian Kristen Faulkner didn’t seriously start riding a bike until 2016 when she needed an outdoor hobby. Shortly after she moved to New York City for a venture capital job, she developed ...
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