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  2. Orlistat - Wikipedia

    en.wikipedia.org/wiki/Orlistat

    Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

  3. Sibutramine - Wikipedia

    en.wikipedia.org/wiki/Sibutramine

    Sibutramine is a serotonin–norepinephrine reuptake inhibitor (SNRI) that, in humans, reduces the reuptake of norepinephrine (by ~73%), serotonin (by ~54%), and dopamine (by ~16%), [ 22] thereby increasing the levels of these substances in synaptic clefts and helping enhance satiety; the serotonergic action, in particular, is thought to ...

  4. Weight loss - Wikipedia

    en.wikipedia.org/wiki/Weight_loss

    Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...

  5. Scientists Just Made a Major Genetic Discovery That Could ...

    www.aol.com/scientists-just-made-major-genetic...

    “The majority of weight loss is because of diet,” he says. “Exercise has a number of benefits, including enhanced weight loss, and it can improve cardiovascular health.”

  6. Pfizer drops twice-daily version of obesity pill over side ...

    www.aol.com/news/pfizer-pulls-plug-twice-daily...

    Pfizer has a once-daily version of the weight-loss pill still in the development. It hopes a change in the drug's release mechanism can reduce side effects, but early data on the new formulation ...

  7. Pfizer's twice-daily weight-loss pill discontinued due to ...

    www.aol.com/news/ozempic-without-injection...

    The weight loss was comparable to that achieved with a 2.4 milligram dose of semaglutide injected once a week in the form of Wegovy over the same time frame, the company said in a statement.

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