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Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Legal status. In Wikidata. Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. The primary role of lipase inhibitors is to decrease the gastrointestinal absorption of fats. Fats then tend to be excreted in feces rather than being absorbed to be ...
Figure 1: During fat digestion, lipases in the gastrointestinal tract hydrolyse fat ( triglycerides) into smaller molecules ( free fatty acids and monoglycerides) which can be absorbed through the duodenal mucosa. Lipase inhibitors bind to lipases and inactivate the enzyme. That leads to excretion of the undigested fat with faeces.
Orlistat (Xenical, Alli). ... Long-term use. Some weight loss pills are intended for short-term use only or may require ongoing monitoring by a healthcare provider. Consider whether this is ...
By increasing levels of these natural chemicals, antidepressants can help change your brain chemistry and, with long-term use, ... Xenical (orlistat) Qsymia (phentermine-topiramate)
When it comes to weight loss, Mounjaro can help those with and without type 2 diabetes lose weight. Doses of 5 milligrams (mg) to 15mg of tirzepatide can help those with type 2 diabetes lose up to ...
Another medication, orlistat, is widely available and approved for long-term use. Its use produces modest weight loss, with an average of 2.9 kg (6.4 lb) at 1 to 4 years, but there is little information on how these medications affect longer-term complications of obesity.
e. Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat. These medications alter one of the fundamental processes of ...
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