Search results
Results from the Tech24 Deals Content Network
Soluble guanylyl cyclase ( sGC) is one of the gasoreceptors for nitric oxide, NO. It is soluble, i.e. completely intracellular. Most notably, this enzyme is involved in vasodilation. In humans, it is encoded by the genes GUCY1A2, GUCY1A3, GUCY1B2 and GUCY1B3 . It is classified under EC number 4.6.1.2.
Soluble guanylate cyclase (sGC) stimulators are a class of drugs developed to treat heart failure, pulmonary hypertension, and other diseases. The first-in-class medication was riociguat, approved in 2013 for pulmonary hypertension. [ 1][ 2] They have also been investigated for hypertension, systemic sclerosis, and sickle cell disease. [ 3][ 1]
Riociguat, sold under the brand name Adempas, is a medication by Bayer that is a stimulator of soluble guanylate cyclase (sGC). It is used to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of the class of sGC ...
Guanylate cyclase 2C (GC-C) is an enzyme expressed mainly in intestinal neurons. Activation of GC-C amplifies the excitatory cell response that is modulated by glutamate and acetylcholine receptors. GC-C, while known mainly for its secretory regulation in the intestinal epithelium, is also expressed in the brain.
Sebaceous carcinoma is a neoplastic growth of sebaceous glands. It is predominantly seen in the head and neck region given the high density of sebaceous glands in this region. The periocular region, which includes the meibomian, Zeis, and sebaceous glands of the caruncle and eyelid, is the most common site accounting for up to 75% of SGc. [ 6]
Structural Genomics Consortium. The Structural Genomics Consortium (SGC) is a public-private-partnership focusing on elucidating the functions and disease relevance of all proteins encoded by the human genome, with an emphasis on those that are relatively understudied. [1] [2] [3] The SGC places all its research output into the public domain ...
The Southern Gas Corridor is an initiative of the European Commission for a natural gas supply route from Caspian and Middle Eastern regions to Europe, proposed in 2008. The goal of the Southern Gas Corridor is to reduce Europe's dependency on Russian gas and add diverse sources of energy supply. [ 1] The route from Azerbaijan to Europe ...
The two priciest cards are baseball cards, followed by three basketball cards . The first sports card to sell for one million dollars was a T206 Honus Wagner which went for $1,265,000 at auction in 2000 (equivalent to $2,238,133 in 2023). [ 1] As of May 2020, the industry brings in over one billion dollars annually for manufacturers and retailers.