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Sominex is the trademarked name for several over the counter sleep aids. Different formulations of Sominex are available, depending upon the market. Both the US and UK formulations contain a significant dose of a first generation antihistamine with hypnotic properties. In the United States, Sominex is marketed by Prestige Brands, [1] sometimes ...
Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
In sleep medicine, we use very small doses of melatonin multiple hours before bed to help gradually shift the body’s clock (circadian rhythm) in people with delayed sleep phase disorder, jet lag ...
Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or delirium.
Zolpidem is a nonbenzodiazepine, or Z-drug, which acts as a sedative and hypnotic. [11][20] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [11] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [11]
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