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rVSV-ZEBOV. VSV-EBOV or rVSV-ZEBOV, sold under the brand name Ervebo, is a vaccine based on the vesicular stomatitis virus which was genetically modified to express a surface glycoprotein of Zaire Ebola virus. [ 16][ 17] In November 2019, the European Commission granted a conditional marketing authorization. [ 18]
In April 2019, following a large-scale ring-vaccination scheme in the DRC outbreak, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no ...
Other current Ebola research is focused on developing treatments or vaccines against the virus. Early investigations into potential vaccines showed that in mice models, the highest levels of protection occurred after vaccination with viral-like particles expressing eVP24. However, at that time the role of eVP24 was still largely unknown.
The vaccine, developed by the pharmaceutical giant Merck, is known as Ervebo. It's the first human Ebola vaccine to be approved by the EU. Ervebo was first engineered by the Public Health Agency ...
A month ago the European Union issued marketing authorization for a vaccine to prevent the Ebola virus in adults, and now the FDA has approved it. While noting that Ebola cases in the US have been ...
Viral vector vaccine. A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material ( DNA) that can be transcribed by the recipient's host cells as mRNA coding for a desired protein, or antigen, to elicit an immune response. [ 1] As of April 2021, six viral vector vaccines, four COVID-19 vaccines and two Ebola ...
An Ebola vaccine has proven to be 100 percent effective during test trials in Guinea. The shot has yet to be approved by a regulator, but Gavi, the Vaccine Alliance, has already committed $5 ...
BY LAURAN NEERGAARD WASHINGTON (AP) -- New monkey studies show that one shot of an experimental Ebola vaccine can trigger fast protection, but the effect waned unless the animals got a booster ...
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