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TKM-Ebola is a combination of small interfering RNAs targeting three of the seven proteins in Ebola virus: Zaire Ebola L polymerase, Zaire Ebola membrane-associated protein (VP24), and Zaire Ebola polymerase complex protein (VP35). [2] [3] By down-regulating these three proteins, TKM-Ebola inhibits virus replication and eliminates the infection.
rVSV-ZEBOV. VSV-EBOV or rVSV-ZEBOV, sold under the brand name Ervebo, is a vaccine based on the vesicular stomatitis virus which was genetically modified to express a surface glycoprotein of Zaire Ebola virus. [ 16][ 17] In November 2019, the European Commission granted a conditional marketing authorization. [ 18]
In April 2019, following a large-scale ring-vaccination scheme in the DRC outbreak, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no ...
The vaccine, developed by the pharmaceutical giant Merck, is known as Ervebo. It's the first human Ebola vaccine to be approved by the EU. Ervebo was first engineered by the Public Health Agency ...
A month ago the European Union issued marketing authorization for a vaccine to prevent the Ebola virus in adults, and now the FDA has approved it. While noting that Ebola cases in the US have been ...
Arbutus Biopharma Corporation is a publicly traded Canadian ( NASDAQ: ABUS) biopharmaceutical company with an expertise in liposomal drug delivery and RNA interference, and is developing drugs for hepatitis B infection. [1] It is headquartered in Warminster, Pennsylvania. [2] The company was formerly known as Tekmira, which was spun out of Inex ...
BY LAURAN NEERGAARD WASHINGTON (AP) -- New monkey studies show that one shot of an experimental Ebola vaccine can trigger fast protection, but the effect waned unless the animals got a booster ...
In December 2016, it was announced that an experimental Ebola vaccine produced by Merck was found to be "highly protective" against the virus after trial runs involving 11,000 people in Guinea. [187] Previously, a 2015 study in medical journal The Lancet reported that the vaccine was 100 percent effective after tests on 4000 people in Guinea ...
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