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In molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated sequence of most frequent residues, either nucleotide or amino acid, found at each position in a sequence alignment. It represents the results of multiple sequence alignments in which related sequences are compared to each other and similar ...
Canonical Wnt pathway Canonical pathway. The canonical Wnt pathway (or Wnt/β-catenin pathway) is the Wnt pathway that causes an accumulation of β-catenin in the cytoplasm and its eventual translocation into the nucleus to act as a transcriptional coactivator of transcription factors that belong to the TCF/LEF family. Without Wnt, β-catenin ...
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein ( mRNA ), or can have a function in and of itself, such as tRNA or rRNA.
Canonical ensemble, in statistical mechanics, is a statistical ensemble representing a probability distribution of microscopic states of the system; Canonical quantum gravity, an attempt to quantize the canonical formulation of general relativity; Canonical stress–energy tensor, a conserved current associated with translations through space ...
Histone. Schematic representation of the assembly of the core histones into the nucleosome. In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei and in most Archaeal phyla. They act as spools around which DNA winds to create structural units called nucleosomes.
Notch-mediated juxtacrine signal between adjacent cells. Notch signaling steps. The Notch signaling pathway is a highly conserved cell signaling system present in most animals. [1] Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. [2] The notch receptor is a single-pass transmembrane receptor ...
Canonical partition function Definition. Initially, let us assume that a thermodynamically large system is in thermal contact with the environment, with a temperature T, and both the volume of the system and the number of constituent particles are fixed. A collection of this kind of system comprises an ensemble called a canonical ensemble.
E-box. An E-box (enhancer box) is a DNA response element found in some eukaryotes that acts as a protein -binding site and has been found to regulate gene expression in neurons, muscles, and other tissues. [1] Its specific DNA sequence, CANNTG (where N can be any nucleotide ), with a palindromic canonical sequence of CACGTG, [2] is recognized ...