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  2. Orlistat - Wikipedia

    en.wikipedia.org/wiki/Orlistat

    Orlistat is used for the treatment of obesity.The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat.

  3. Lipase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Lipase_inhibitors

    In Wikidata. Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. The primary role of lipase inhibitors is to decrease the gastrointestinal absorption of fats. Fats then tend to be excreted in feces rather than being absorbed to be used as a ...

  4. Discovery and development of gastrointestinal lipase ...

    en.wikipedia.org/wiki/Discovery_and_development...

    [5] [8] [9] For that reason orlistat was chosen over lipstatin for development as an anti-obesity drug. [1] [10] It is the only available FDA-approved oral lipase inhibitor and is known on the market as Xenical and Alli. [5] Initially orlistat was developed as a treatment for dyslipidemia, not as an anti-obesity agent. When researchers found ...

  5. What Is the Strongest Weight Loss Prescription Pill? - AOL

    www.aol.com/strongest-weight-loss-prescription...

    Orlistat (Xenical, Alli). Orlistat works by preventing your body from absorbing dietary fats. It inhibits lipase, an enzyme in the intestine that breaks down fat molecules. This leads to reduced ...

  6. Wegovy and other weight loss drugs shows promise for heart ...

    www.aol.com/news/wegovy-shows-promise-heart...

    The weight-loss drug Wegovy can reduce the risk of heart attacks and strokes by 20% in adults with heart disease and obesity, according to new research. ... like phentermine or orlistat, have not ...

  7. Can Antidepressants Cause Weight Loss? - AOL

    www.aol.com/antidepressants-cause-weight-loss...

    However, many are associated with an infamous side effect: weight gain. Luckily, some antidepressants are less likely to cause weight gain than others. In fact, there are even some antidepressants ...

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