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Neurogenic claudication commonly describes pain, weakness, fatigue, tingling, heaviness and paresthesias that extend into the lower extremities. [9] These symptoms may involve only one leg, but they usually involve both. Leg pain is usually more significant than back pain in individuals who have both. [12]
[26] [27] About 15–30% of people living with migraine experience episodes with aura, [13] [28] and they also frequently experience episodes without aura. [29] The severity of the pain, duration of the headache, and frequency of attacks are variable. [26] A migraine attack lasting longer than 72 hours is termed status migrainosus. [30]
Hemiplegia, in its most severe form, is the complete paralysis of one entire side of the body. Either hemiparesis or hemiplegia can result from a variety of medical causes, including congenital conditions, trauma, tumors, traumatic brain injury and stroke.
New York headquartered Kaia Health, which offers AI-assisted digital therapies via a mobile app for chronic pain related to musculoskeletal (MSK) disorders and for Chronic Obstructive Pulmonary ...
Most pain resolves once the noxious stimulus is removed and the body has healed, but it may persist despite removal of the stimulus and apparent healing of the body. Sometimes pain arises in the absence of any detectable stimulus, damage or disease. [3] Pain is the most common reason for physician consultation in most developed countries.
Pain, swelling, or stiffness in one or more joints is commonly present in psoriatic arthritis. [4] Psoriatic arthritis is inflammatory, and affected joints are generally red or warm to the touch. [4] Asymmetrical oligoarthritis, defined as inflammation affecting two to four joints during the first six months of disease, is present in 70% of ...
The crude prevalence rate of PD has been reported to range from 15 per 100,000 to 12,500 per 100,000, and the incidence of PD from 15 per 100,000 to 328 per 100,000, with the disease being less common in Asian countries. PD is primarily characterized by death of dopaminergic neurons in the substantia nigra, a region of the midbrain. The cause ...
It is conjugated in the kidney for excretion in the urine, where 75% of the drug is excreted, [114] and about 15% is eliminated in feces. [ 115 ] : 430 Desmethylmirtazapine is an active metabolite of mirtazapine which is believed to contribute about 3-10% to the drugs overall effects and has a half-life of about 25 hours.
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