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  2. History of hypertension - Wikipedia

    en.wikipedia.org/wiki/History_of_hypertension

    The term essential hypertension ('Essentielle Hypertonie') was coined by Eberhard Frank in 1911 to describe elevated blood pressure for which no cause could be found. [ 11] In 1928, the term malignant hypertension was coined by physicians from the Mayo Clinic to describe a syndrome of very high blood pressure, severe retinopathy and inadequate ...

  3. Antihypertensive drug - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive_drug

    Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of dementia ...

  4. Angiotensin-converting enzyme - Wikipedia

    en.wikipedia.org/wiki/Angiotensin-converting_enzyme

    View/Edit Mouse. Angiotensin-converting enzyme ( EC 3.4.15.1 ), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood ...

  5. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

  6. Adrenocorticotropic hormone deficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic...

    Glucocorticoids. [ 2] Adrenocorticotropic hormone deficiency is a rare disorder characterized by secondary adrenal insufficiency with minimal or no cortisol production and normal pituitary hormone secretion apart from ACTH. [ 3] ACTH deficiency may be congenital or acquired, and its symptoms are clinically similar to those of glucocorticoid ...

  7. Arthritis - Wikipedia

    en.wikipedia.org/wiki/Arthritis

    Arthritis is the most common cause of disability in the United States. More than 20 million individuals with arthritis have severe limitations in function on a daily basis. [ 12] Absenteeism and frequent visits to the physician are common in individuals who have arthritis. Arthritis can make it difficult for individuals to be physically active ...

  8. Refractory Hypertension - Wikipedia

    en.wikipedia.org/wiki/Refractory_hypertension

    Refractory Hypertension. Refractory hypertension (RfHTN) is hypertension, a high blood pressure, that remains uncontrolled on maximal or near-maximal therapy, that includes the use of ≥5 antihypertensive agents of different classes. [1] Agents used include a long-acting thiazide-like diuretic (such as chlorthalidone) and spironolactone. [2]

  9. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    e. Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. [ 11] High blood pressure usually does not cause symptoms itself. [ 1] It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral ...

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