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Glucocorticoids. [ 2] Adrenocorticotropic hormone deficiency is a rare disorder characterized by secondary adrenal insufficiency with minimal or no cortisol production and normal pituitary hormone secretion apart from ACTH. [ 3] ACTH deficiency may be congenital or acquired, and its symptoms are clinically similar to those of glucocorticoid ...
Autoimmune hemolytic anemia ( AIHA) is an autoimmune disorder which occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst ( lyse ), leading to an insufficient number of oxygen-carrying red blood cells in circulation ( anemia ). The lifetime of the RBCs is reduced from the normal 100–120 days to ...
Anemia of inflammation. Anemia of inflammatory response. Anemia of chronic disease ( ACD) [ 1][ 2] or anemia of chronic inflammation[ 3] is a form of anemia seen in chronic infection, chronic immune activation, and malignancy. These conditions all produce elevation of interleukin-6, which stimulates hepcidin production and release from the liver.
β-endorphin. β-MSH. Adrenocorticotropic hormone ( ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. [ 1] It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in ...
1 per 1000 people [ 8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [ 5] Those affected often have a gradual onset. [ 5] The most common initial symptoms are feeling tired and weak. [ 4]
The most common cause of primary adrenal insufficiency (Addison's disease) overall is autoimmune adrenalitis. [2] The prevalence of Addison's disease ranges from 5 to 221 per million in different countries. [30] In children, congenital adrenal hyperplasia (CAH) is the most common cause of adrenal insufficiency, with an incidence 1 in 14,200 ...
Rheumatoid arthritis ( RA) is a long-term autoimmune disorder that primarily affects joints. [ 1] It typically results in warm, swollen, and painful joints. [ 1] Pain and stiffness often worsen following rest. [ 1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [ 1]
6947. Iron-deficiency anemia (or iron deficiency anaemia) is a common anemia that occurs when iron loss (often from intestinal bleeding or menses) occurs, and/or the dietary intake or absorption of iron is insufficient. In such a state, hemoglobin, which contains iron, cannot be formed. [ 5] Plummer–Vinson syndrome.