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  2. Prescription weight-loss drugs: Can they help you? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    Prescription weight-loss drugs that you can use for more than 12 weeks, called long-term use, lead to major weight loss compared with an inactive treatment that doesn't use medicine, called a placebo. The combination of weight-loss medicine and lifestyle changes leads to greater weight loss than do lifestyle changes alone.

  3. Semaglutide (Subcutaneous Route) Side Effects - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/semaglutide...

    Semaglutide injection is also used together with diet and exercise to help lose weight and keep the weight off in patients with at least one weight-related medical condition. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Solution; Before Using

  4. GLP-1 agonists: Diabetes drugs and weight loss - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/type-2-diabetes/...

    These include canagliflozin (Invokana), ertugliflozin (Steglatro), dapagliflozin (Farxiga) and empagliflozin (Jardiance). Weight loss can vary depending on which GLP-1 drug you use and your dose. Studies have found that all GLP-1 drugs can lead to weight loss of about 10.5 to 15.8 pounds (4.8 to 7.2 kilograms, or kg) when using liraglutide.

  5. Vitamin B-12 injections for weight loss: Do they work? - Mayo...

    www.mayoclinic.org/healthy-lifestyle/weight-loss/expert...

    There's no solid proof that vitamin B-12 shots, also called injections, help you lose weight. Vitamin B-12 is a water-soluble B complex vitamin. It's found naturally in many foods, such as meat, fish and dairy products. Vitamin B-12 is added to some foods and is available as a dietary supplement. Health care providers commonly prescribe vitamin ...

  6. HCG diet: Is it safe and effective? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/expert...

    Answer From Katherine Zeratsky, R.D., L.D. No. The HCG diet isn't safe, and it doesn't lead to long-term weight loss. HCG stands for human chorionic gonadotropin. It's a hormone made in the body during pregnancy. Lab-made HCG is added to some weight-loss products that are sold without a prescription. The U.S. Food and Drug Administration (FDA ...

  7. Weight-loss surgery: Is it an option for you? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    The general medical guidelines for weight-loss surgery are based on body mass index (BMI). BMI is a formula that uses weight and height to estimate body fat. Weight-loss surgery might be an option for an adult with a BMI of 40 or higher. The surgery may also be an option for an adult who meets these three conditions: BMI of 35 or higher.

  8. Semaglutide (Subcutaneous Route) Proper Use - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/semaglutide...

    For weight management and lowering the risk of heart attack or stroke: For injection dosage form (Wegovy® solution): Adults and children 12 years of age and older—At first, 0.25 milligrams (mg) injected under the skin once a week for 4 weeks. Your doctor may increase your dose every 4 weeks.

  9. Insulin and weight gain: Keep the pounds off - Mayo Clinic

    www.mayoclinic.org/.../insulin-and-weight-gain/art-20047836

    The link between insulin and weight gain. When you take insulin, sugar can enter your cells. This makes the sugar levels in your blood go down. This is the goal of treatment. But if you take in more calories than you need to keep a healthy weight, your cells will get more sugar than they need. This happens in people who don't have diabetes, too.

  10. Alli weight-loss pill: Does it work? - Mayo Clinic

    www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/...

    Alli is a 60-milligram, over-the-counter version of orlistat (Xenical), a 120-milligram prescription drug. Both Alli and Xenical are meant to be used as part of a weight-loss plan, along with a low-calorie, low-fat diet and regular physical activity. Alli is approved by the U.S. Food and Drug Administration for use in adults 18 and older who ...

  11. Use of weight-loss pharmacotherapy in patients with cirrhosis and...

    www.mayoclinic.org/medical-professionals/digestive...

    The four weight-loss medications currently approved by the FDA for treatment of obesity are orlistat, phentermine-topiramate, naltrexone-bupropion and liraglutide. Although some society guidelines have endorsed the use of these medications in patients with cirrhosis or in liver transplant recipients, they have not yet been widely used in this ...